Detective Reuben "Diego" Montoya must team up with the prime suspect in a murder case to catch a serial killer who is keeping New Orleans in the grip of fear, an investigation that leads them to an abandoned asylum where unspeakable evil awaits them.

In present-day New Orleans, Polly Deschamps finds herself at yet another lonely crossroads in her life until she encounters architect Marshall Marchand, a lifelong bachelor who spends most of his time with his brother Danny. When Polly's two young daughters from her previous marriage are likewise taken with Marshall, she marries him. But then an ominous prediction by a New Orleans tarot card reader proclaims that Polly will murder her husband, and...

Shortly after her mother's death, nurse Karen Whitlaw receives a notebook from her father, a Vietnam vet who abandoned her years before. She then learns from New Orleans detective Marc Chastain that her father has been killed. As Karen and Marc become involved, someone threatens Karen's life.

A New Orleans lawyer kills himself, and the suicide is witnessed by Mark Sway, a bright 11-year-old boy, who overhears from the dying man a deadly secret about a Louisiana senator's murder. The accused killer, Mafia thug Barry Muldanno, is about to go on trial. Mark hires a lawyer, Reggie Love, and comes up with a plan.

After arriving in America as an Irish nurse, banshee Caer Donahue yearns for a mortal life when she is submerged in a mystery of sunken treasure and attempted murder, which leads her into the loving arms of Zach Flynn.

An ancient Celtic warrior cursed by a god to bring death to any woman he loves, Talon, a seductive vampire, prowls the night, serving as a protector of the innocent, until in modern-day New Orleans, a runaway Mardi Gras float brings him face to face with the outrageous Sunshine Runningwolf.

When a copy of his first wife's death certificate arrives in the mail, emblazoned with a red question mark, New Orleans detective Rick Bentz follows the postmark trail to Los Angeles, returning to the painful memories he's tried so hard to forget, and straight into a killer's web that catches Bentz as the prime suspect.