When Fluffy the class guinea pig goes home with Wade for the weekend, Wade loses a tooth and Fluffy learns about the Tooth Fairy.

When the kindergarten classroom gets a pet guinea pig Eliza is afraid, but when the guinea pig gets lost, Eliza helps find her.

Guinea pig Sasspants knows something is wrong with ninth-grader Viola, the new pet shop assistant, so when Mr. Venezi goes missing Sasspants and Hamisher put their private investigation skills to the test.

"The laughs continue when Fido, the guinea pig that thinks she's a dog, has a pup that thinks she's a squirrel. A sequel to Guinea Dog"--

When Ms. Day's class takes a field trip to an apple orchard, Fluffy the guinea pig goes along, but will he ever get to eat his apple?

When guinea pig Sasspants leaves Mr. Venezi's pet shop to live with Detective Nichols, and hamster-detective Hamisher retires, the case of the missing bookstore cat must be solved without their help.